background Atypical fibroxanthoma (AFX) is an uncommon spindle cell neoplasm occurring most often in actinically damaged skin of elderly patients. This tumor has invasive potential, may recur locally after excision, and rarely metastasizes. To conserve tissue and improve the likelihood of cure, Mohs micro–graphic surgery (MMS) has been used for treatment.
31 Jul 2019 Atypical fibroxanthoma is often considered a skin cancer of the elderly. Typically Mohs surgery for lesions located on the head, neck or other.
Atypical fibroxanthoma (AFX) is an uncommon, pleomorphic, spindle cell cutaneous malignancy that most commonly presents as a solitary red or pink papule or nodule on the head or neck . Exposure to ultraviolet light most likely contributes to the development of AFX. Atypical fibroxanthoma: a series of 56 tumors and an unexplained uneven distribution of cases in southeast Germany. Wollina U(1), Schönlebe J(2), Ziemer M(3), Friedling F(4), Koch A(1), Haroske G(2), Kaatz M(4), Simon JC(3). 2020-10-14 · Atypical fibroxanthoma (AFX) is a tumor that occurs primarily in older individuals after the skin of the head and neck has been damaged significantly by sun exposure and/or therapeutic radiation. Atypical fibroxanthoma demonstrates an uneven geographic distribution in southeast Germany that demands further investigations. Mohs surgery with ≥2 cm safety margins is the treatment of choice. A regular follow‐up is recommended.
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AFX usually involves sites of high cumulative ultraviolet exposure and is rarely located in the periocular region. We are aware of 7 case reports in the literature, of periocular AFX, one of which was treated with Mohs Micrographic Surgery (MMS). 2020-10-14 Atypical fibroxanthoma (AFX) and pleomorphic dermal sarcoma (PDS) tumors share many clinical, etiologic, and histologic features and likely represent components of a tumor spectrum. In dermatologic oncology, differentiating between AFX and PDS is pivotal as tumors with histological features consistent with PDS are more likely to behave in a clinically aggressive manner. What is Atypical Fibroxanthoma?
Atypical fibroxanthoma (AFX). Espino-Ardila C(1), Goldberg LH. Author information: (1)DermSurgery Associates, Houston, TX, USA 2019-11-08 Atypical fibroxanthoma and undifferentiated pleomorphic sarcoma, or pleomorphic dermal sarcoma, are rare malignant cutaneous neoplasms existing along a clinicopathologic spectrum.
Atypical fibroxanthoma: a series of 56 tumors and an unexplained uneven distribution of cases in southeast Germany. Wollina U(1), Schönlebe J(2), Ziemer M(3), Friedling F(4), Koch A(1), Haroske G(2), Kaatz M(4), Simon JC(3).
AFX appears clinically as a discrete red or pink nodule or papule …. Atypical fibroxanthoma (AFX) is a dermal 2016-11-01 Atypical fibroxanthoma: a series of 56 tumors and an unexplained uneven distribution of cases in southeast Germany. Wollina U(1), Schönlebe J(2), Ziemer M(3), Friedling F(4), Koch A(1), Haroske G(2), Kaatz M(4), Simon JC(3). Atypical fibroxanthoma demonstrates an uneven geographic distribution in southeast Germany that demands further investigations.
Background Atypical fibroxanthoma is a rare mesenchymal tumor of the head and neck region.Methods We analyzed the files of 3 large dermatology hospitals from the years 2001 to 2013 in southeast
It occurs mainly on the head or neck of older people, usually after the skin has been damaged by prolonged exposure to sunlight. What causes Atypical Fibroxanthoma? What is atypical fibroxanthoma? Atypical fibroxanthoma is a type of skin cancer which is often misdiagnosed as a less serious skin condition. Normally, cells in the body will grow and divide to replace old or damaged cells.
Mohs micrographic surgery was performed in May 2006 and no recurrence was noted in one year of
Mohs Micrographic Surgery differs from wide local excision in that it removes skin cancer one small layer at a time. Each layer removed is then analyzed under a
7 Apr 2021 Atypical fibroxanthoma relapse as pleomorphic dermal sarcoma after slow Mohs micrographic surgery Conflict of interest: None. Funding source
15 Jul 2020 Atypical fibroxanthoma (AFX); Pleomorphic dermal sarcoma (PDS); Superficial malignant fibrous histiocytoma (MFH); Undifferentiated
Diagnosis of atypical fibroxanthoma is with biopsy. Tumors are excised, or Mohs micrographic surgery—in which tissue borders are progressively excised until
10 Sep 2020 Atypical fibroxanthoma is a rare, low-grade superficial sarcoma that Previously, this utilized 1 cm margins, however Mohs micrographic
However, AFX is the most common tumor of the skin other than basal cell cancer, squamous cell cancer, and melanoma seen by Mohs surgeons. Elderly, light-
Background: Atypical fibroxanthoma (AFX) is a fibrohistiocytic tumor with relatively high local recurrence rates but low metastatic potential. Wide local excision (
Atypical fibroxanthoma (AFX) is a rare primary mesenchymal skin tumor of presumable WLE: Wide local excision; MMS: Mohs micrographic surgery.
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dermatofibrosarcoma protuberance, atypical fibroxanthoma, Merkel cell with wide margins or Mohs micrographic surgery (MMS) is recommended45. icke-radikala excisioner av hudtumörer Förbättrade indikationer för Mohs kirurgi vid basalcellscancer i huvud- och halsregionen Immunhistokemisk detektion Features eight all-new chapters on Atypical Fibroxanthoma, Confluent and Reticulated Mohs Surgery Appropriate Use Criteria. Medicin.
Methods We analyzed the files of 3 large dermatology hospitals from the years 2001 to 2013 in southeast Germany.
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Background. Atypical fibroxanthoma (AFX) is a fibrohistiocytic tumor with relatively high local recurrence rates but low metastatic potential. Wide local excision (WLE) and Mohs micrographic surgery (MMS) are common treatments, although no consensus exists regarding optimal therapy.
Jacobs DS, Edwards WD, Ye RC. Metastatic atypical fibroxanthoma of skin. Cancer 1975;35:457-463.